Fatty acid synthetase from a mouse mammary adenocarcinoma.
نویسندگان
چکیده
Fatty acid synthetase was isolated from transplantable mammary adenocarcinomas carried by C3H mice. Comparison of physicochemical and immunological properties of this enzyme with those of the fatty acid synthetase isolated from normal glands of lactating C3H mice indicates that the enzymes are similar in all respects. The products of the purified fatty acid synthetase from normal and neoplastic tissues were the same, mainly long-chain fatty acids. The normal gland was found to contain 30 times more enzymes per g tissue than did the neoplasm; this may account in part for the relatively low rat of fatty acid synthetase found previously in this neoplasm.
منابع مشابه
Fatty Acid Synthetase from a Mouse Mammary Adenocarcinoma
Fat ty acid synthetase was isolated from transplantable m a m m a r y adenocarcinomas carried by C3H mice. Comparison of physicochemical and immunological properties of this enzyme with those of the fatty acid synthetase isolated from normal glands of lactating C3H mice indicates that the enzymes are similar in all respects. The products of the purified fatty acid synthetase from normal and neo...
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Fatty acid synthetase purified from the mammary gland of the rabbit has a mol. wt. of 968000 as determined by gel filtration. The enzyme gave one band, corresponding to a mol.wt. of approx. 35000, on polyacrylamide-gel electrophoresis in the presence of sodium dodecyl sulphate and phenylmethanesulphonyl fluoride.
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عنوان ژورنال:
- Cancer research
دوره 35 11 Pt 1 شماره
صفحات -
تاریخ انتشار 1975